Impact of Glucose on Amylin levels in SH-SY5Y Cells

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Abstract Summary

There is a known link between Diabetes, specifically type two, and the development of Alzheimer's Disease. While studies have not yet been able to determine whether greater amounts of insulin cause Alzheimer’s Disease, the idea that this phenomenon may occur has inspired us to explore how UCP2 affects amylin and insulin secretion. UCP2 has been found to aid in cell signaling in both neuronal and pancreatic beta-cells. The presence of UCP2 in both cells is significant because it indicates the relationship between the pancreas and the brain and aids in the regulation of metabolism and satiety.

Abstract ID :
2019-376
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Spelman College
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Spelman College

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